An effective and additional treatment to fight cancer.

  • What's Hyperthermia?
    Hyperthermia consists in the focused application of thermic energy (heat) in the treatment of diseases. The use of hyperthermia as a therapy in the cancer treatment is documented since ancient times (Hippocrates, 460 BC.) and, a few years ago, it was possible to design technology and equipment able to apply the heat in a specific and efficient way for the patient. Hyperthermia's goal in cancer treatment is to raise the tumor's temperature above the normal physiological levels, causing an imbalance in the cellular structure, which weakens the tumor and destroys it in some cases.

  • How does Hyperthermia work?
    • Powerful sensitizer:
      By combining hyperthermia with chemotherapy and/or radiotherapy treatments, hyperthermia acts as a powerful sensitizer, improving the response rates of these treatments and the survival rates for these patients.
    • Hyperthermia techniques
      There are several hyperthermia techniques, classified according to their invasion or penetration level in the body and to their method of application. Hyperthermia with Celsius TCS is local, not invasive, it can be superficial or deep and is applied capacitively by means of an electromagnetic field. This means that the tumor, either superficial or deep, is heated selectively by the device from the outside, without pain and without affecting the adjacent tissue or skin of the patient.
    • Clinical effect
      The heat transmitted to the tumor by the Celsius TCS device weakens and can even destroy the cancer cells in a way that the adjacent healthy cells are not affected and remain safe. This can happen by:
      • Directly weakening the tumor cells with heat;
      • Increasing the blood flow through the weakened tumor, allowing the cytostatic to enter the tumor and attach it from the inside as well as from the exterior;
      • Increasing the oxygen levels thanks to its increment in the blood flow so that the cancer can be treated more effectively with radiation;
      • Activating the immune system of the patient because, when detecting the local temperature raise, the body will activate the immune system and attack the cancer cells.
    • The therapy
      Hyperthermia with Celsius TCS is a treatment performed in several sessions and is programed by the oncologist. Depending on the type of disease, each patient undergoes between 1 to 14 treatment sessions. Each session lasts approximately 60 minutes and has no side effects for the patient. Hyperthermia sessions can be performed before, during or after a chemotherapy or radiotherapy treatment, dependent on the clinician's assessment and judgment.
    • Procedure
      1. The patient lays down in the treatment bed. The bed is divided in 21 spaces and includes an inferior electrode which is adjustable and can be positioned according to the target body part.
      2. Both electrodes start emitting and receiving radiofrequency waves. The polarity difference of the healthy cells and the cancer cells will result in the waves being absorbed by the cancer cells only, they will begin to vibrate, collide and slowly heat up to temperatures above 40 ºC.
      3. During each session, the patient holds a pause device to stop the treatment at any time in case of discomfort. When the patient is ready to resume the treatment, they can press the button again and restart. The patient is always awake and can maintain a conversation with the doctor or nurse who administered the treatment.

  • Adverse effects and contraindications
    • Adverse effects
      • Unlike surgery, chemotherapy and radiotherapy, hyperthermia doesn't present any significant side effects;
      • Upon completion of the hyperthermia session, patients feel good due to the warm sensation, though they can feel tired. Rarely, the destruction of the cancer cells can result in a slight fever of the patient. Both effects are considered a good response to the treatment.
    • Contraindications
      Hyperthermia with Celsius TCS is not indicated in:
      • Individuals with coronary bypass and its electrodes;
      • Individuals with metallic prosthesis placed near the treatment site of the tumor.

  • Reference in the application of hyperthermia:
    Dr. António Moreira Pinto, Medical Oncology Specialist, Head of Hyperthermia Treatment at CUF Porto Hospital with the Celsius 42 device.